In the present experiment, the effects of acetyl-L carnitine and L carnitine on the levels of free, acyl, and total L-carnitine in plasma and brain, rat ambulatory activity, and biomarkers of oxidative stress are investigated. Aged rats were given acetyl-L carnitine or L-carnitine at 0.15% in drinking water for 4 weeks. L-carnitine and acetyl-L carnitine were similar in elevating carnitine levels in plasma and brain.
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